Catalytic radiopharmaceuticals unlock immune memory by rewiring tumor metabolism
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REFERENCES
[1] Yang M.-D., Zhu C.-Y., Yang G., et al. (2025). Camouflaged membrane-bridged radionuclide/Mn single-atom enzymes target lipid metabolism disruption to evoke antitumor immunity. Mil. Med. Res. 12:59. DOI:10.1186/s40779-025-00647-7 [2] Sgouros G., Bodei L., McDevitt M. R., et al. (2020). Radiopharmaceutical therapy in cancer: clinical advances and challenges. Nat. Rev. Drug Discov.19:589−608. DOI:10.1038/s41573-020-0073-9 [3] Guo S., Yao Y., Tang Y., et al. (2023). Radiation-induced tumor immune microenvironments and potential targets for combination therapy. Signal Transduction Targeted Ther. 8:205. DOI:10.1038/s41392-023-01462-z [4] Quazi T. H. S. (2023). Iron oxide nanoparticles in magnetic drug targeting and ferroptosis-based cancer therapy. Med. Rev. 3:444−447. DOI:10.1515/mr-2023-0029 [5] Pan H., Yang S., Gao L., et al. (2024). At the crossroad of nanotechnology and cancer cell membrane coating: Expanding horizons with engineered nanoplatforms for advanced cancer therapy harnessing homologous tumor targeting. Coord. Chem. Rev. 506:215712. DOI:10.1016/j.ccr.2024.215712 -
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Pan H., Yang S., Zheng X., et al. (2026). Catalytic radiopharmaceuticals unlock immune memory by rewiring tumor metabolism. The Innovation Drug Discovery 1:100004. https://doi.org/10.59717/j.xinn-drugdisc.2026.100004
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Pan H., Yang S., Zheng X., et al. (2026). Catalytic radiopharmaceuticals unlock immune memory by rewiring tumor metabolism. The Innovation Drug Discovery 1:100004. https://doi.org/10.59717/j.xinn-drugdisc.2026.100004
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Figure 1.
Schematic diagram of the construction of 131I-Mn/SAE@M and its mechanism in disrupting tumor lipid metabolism and remodeling the tumor immune microenvironment
